MET
Metabolic
GLP-1 and amylin analogs. The only group in this category with large completed human trials behind it, and the only one where the regulator has already acted.
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INDEPENDENT RESEARCH COVERAGE · NOTHING FOR SALE
Most of these compounds were never tested in people.
BRAK Labs covers what each peptide is, what the studies actually found, and what nobody knows yet. Where the evidence is thin we say so on the first line of the page. That is most of the time.
Click any node to name the compound it carries.
field compounds · links · 0 opened
“We publish what the studies found, including when they found nothing. A compound with no human trials gets a page that says so in the first sentence.”
Editorial policy (placeholder text, pending the standards doc)
coverage
Four groups, graded the same way
Every compound gets the same treatment: what it is, what was studied, what the study actually showed, and where the regulator stands today. Nothing here tells anyone to take anything, and no page carries a dose.
REP
Repair and recovery
Tissue-repair compounds. The best-selling group in the market and among the thinnest on human evidence, which is the single most useful fact a reader can leave with.
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GHS
Secretagogues
Growth-hormone-releasing peptides and ghrelin-receptor agonists. Mostly studied as short endocrine experiments rather than as anything a person would use.
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LNG
Longevity and cognitive
Bioregulators and neuropeptides. The least-evidenced group we cover, and the one where marketing copy and published research diverge the furthest.
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compounds
The index
Six shown. Each card carries the group, the evidence grade, how many registered human trials exist, and the regulatory position. The grade comes before the description on purpose.
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REPunapproved
BPC-157
Pentadecapeptide BPC, 15 amino acids
- evidence
- D
- human trials
- 2
- status
- 503A cat. 2
The best-selling compound in the category has no completed, published human efficacy trial. The evidence is rodent work, most of it from one research group.
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REPunapproved
TB-500
Thymosin beta-4 fragment, 7 amino acids
- evidence
- C
- human trials
- 18
- status
- unapproved
The trials exist, but they studied dry eye and corneal wound healing. None of them looked at the muscle and tendon use it is sold for.
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METapproved drug
Semaglutide
GLP-1 receptor agonist, 31 amino acids
- evidence
- A
- human trials
- many
- status
- approved
The best-evidenced compound on this list, and the only one that reached approval. Both facts belong on the same page.
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LNGunapproved
GHK-Cu
Copper tripeptide-1, 3 amino acids
- evidence
- TBD
- human trials
- placeholder
- status
- cosmetic
Placeholder copy. The topical cosmetic literature and the injected research literature are two different bodies of work, and readers conflate them constantly.
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GHSunapproved
Ipamorelin
Ghrelin-receptor agonist, 5 amino acids
- evidence
- TBD
- human trials
- placeholder
- status
- unapproved
Placeholder copy. Grade and trial count are pending the literature pass, and this card stays marked until they land.
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LNGunapproved
KPV
Alpha-MSH fragment, 3 amino acids
- evidence
- TBD
- human trials
- placeholder
- status
- unapproved
Placeholder copy. Almost nobody is writing about this one, which is the reason it sits near the top of the list.
Grades and trial counts marked placeholder are filler. The unmarked ones are real and dated, and every guide page carries the date it was last checked.
evidence
How the grades work
One scale, applied the same way to every compound, published so anyone can check it. A grade describes the quality of the research, not whether something works and not whether anyone should use it.
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GRADE A
Completed phase 3
large, published, replicated
Multiple completed trials in people, published, with results that hold up across more than one program. Very few compounds in this category reach it.
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GRADE B
Real program, unfinished
phase 2 or 3 underway
A genuine trial program exists and some of it has read out, but the answer is not settled or the trials tested something other than the marketed use.
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GRADE C
Human data, wrong question
studied, but not for this
People have been studied, but for a different condition or by a different route than the one it is sold for. Common, and the easiest grade to misread.
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GRADE D
Animals and anecdote
no completed human trial
Rodent studies, case reports, forum accounts. Sometimes a lot of rodent studies. It is still not evidence that something works in a person.
the gap
Completed human efficacy trials for the best-selling compound
Completed, published human efficacy trials for BPC-157:
0
Zero. The single best-selling compound in this category has never completed a published trial in people. Two are registered: one phase 1 from 2015 whose status is unknown, and one phase 2 now recruiting. Everything sold today rests on animal studies and forum reports. Sites that quietly leave that out are how a reader ends up believing the opposite.
- registered trials
- 2
- completed and published
- 0
- evidence grade
- D
guides
Recent guides
Every guide is dated, every claim carries a citation, and every page says who checked it. Corrections stay visible at the bottom of the page instead of being edited away.
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GUIDE 01
[REP · grade D]BPC-157: what the research actually shows
Where the rodent work came from, what the two registered human trials are, and why the gap between the two matters.
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GUIDE 02
[REP · grade C]TB-500 and thymosin beta-4 are not the same claim
Eighteen trials exist. They studied eyes and skin. Nothing published looked at the use it is marketed for.
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GUIDE 03
[safety]Are research peptides safe? What is known and what is not
Short-answer page for the most common question in the category, written without a dose, a protocol, or a recommendation.
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GUIDE 04
[MET · grade A]Why the best-evidenced peptides ended up behind a prescription counter
Approval, compounding, and the enforcement history that separated the studied compounds from the rest.
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GUIDE 05
[method]How to read a certificate of analysis
What a purity number proves, what it does not, and which parts of a certificate are worth checking.
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